History

HISTORY OF NARCOLEPSY

  • 1870’s – Syndrome first described
  • 1930’s – Stimulant treatments
  • 1950’s – Sleep-onset REM periods
  • 1970’s – Canine model
  • 1980’s – Association with immune related human leukocyte antigens (HLA)
  • 2000’s – Discovery of canine gene and lack of hypocretin in human narcolepsy
  • 2010’s – Autoimmune basis of narcolepsy
  • 2020’s – Hypocretin agonists and prevention.

2020 is of course the future and a goal for scientists worldwide to reach.

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