History

HISTORY OF NARCOLEPSY

1870’s – Syndrome first described
1930’s – Stimulant treatments
1950’s – Sleep-onset REM periods
1970’s – Canine model
1980’s – Association with immune related human leukocyte antigens (HLA)
2000’s – Discovery of canine gene and lack of hypocretin in human narcolepsy
2010’s – Autoimmune basis of narcolepsy
202?’s – Hypocretin agonists and prevention.
202? is of course the future and a goal for scientists worldwide to reach.