Idiopathic Hypersomnia

Idiopathic Hypersomnia Menu

Idiopathic hypersomnia is a neurological sleep disorder characterized by excessive daytime sleepiness, difficulty waking up, and a lack of refreshment from naps. Below is a detailed menu explaining the condition:

1. Symptoms

– Excessive Daytime Sleepiness: Feeling extremely tired during the day despite adequate nighttime sleep.

– Sleep Inertia: Waking up confused and disoriented, often referred to as “sleep drunkenness.”

– Long Sleep Duration: Sleeping more than 11 hours per night.

– Unrefreshing Naps: Taking naps that do not improve alertness.

– Cognitive Impairments: Difficulty with memory and attention.

– Emotional Changes: Anxiety, irritability, and mood swings

2. Diagnose

– Medical History: Reviewing personal and family medical history.

– Physical Exam: Conducting a thorough physical examination.

– Sleep Studies: Polysomnography and multiple sleep latency tests to assess sleep patterns.

– Questionnaires: Using tools like the Epworth Sleepiness Scale to evaluate sleepiness levels

3. Treatment

– Medications: Stimulants like modafinil and armodafinil to reduce daytime sleepiness.

– Lifestyle Changes: Maintaining a regular sleep schedule, avoiding alcohol, and avoiding activities that disrupt sleep patterns.

– Cognitive Behavioral Therapy for Hypersomnia (CBT-H): A form of psychotherapy to improve sleep quality and daily functioning

4. Medication

– Stimulants: Modafinil (Provigil), Armodafinil (Nuvigil), and Methylphenidate.

– Sodium Oxybate: Used to promote deep sleep and reduce daytime sleepiness.

– Other Options: Pitolisant (Wakix) and newer wake-promoting agents like solriamfetol

5. Causes

– Genetics: Family history plays a significant role.

– Nervous System Dysfunction: Possible issues with the autonomic nervous system.

– Autoimmune Disease: Symptoms may appear after a viral illness.

– Neurotransmitter Imbalance: Increased GABA-A activity may contribute to sleepiness

6. History

– First Described in 1976: Initially identified as polysymptomatic and monosymptomatic forms.

– Evolution of Diagnostic Criteria: Changes over the years to better define the condition.

– Current Understanding: Recognized as a heterogeneous disorder with unclear prevalence due to lack of biomarkers